Endocrine Abstracts

Background:With respect to what has been mentioned about the progression of IGT to overt diabetes, and the lack of information in rural areas, and also some unresolved questions about the relationship between IGT and some micro and macrovascular complications, this research was accomplished in the years 2001-2002.Material and Methods:The first step of this study was carried out in 1977 to screen people (1988 ...

Background:With respect to what has been mentioned about the progression of IGT to overt diabetes, and the lack of information in rural areas, and also some unresolved questions about the relationship between IGT and some micro and macrovascular complications, this research was accomplished in the years 2001-2002.Material and Methods:The first step of this study was carried out in 1977 to screen people (1988 ...

Introduction: Methimazole is a widely prescribed antithyroid drug for the treatment of hyperthyroidism with a few adverse effects generally well-tolerated. However, methimazole-induced cholestatic jaundice (CJ) is a rare but serious adverse reaction. Herein we report a rare case of methimazole-induced CJ in a woman with hyperthyroidism.Case report: A 57-years-old women presented to our endocrinology department with a 2-week history of asthenia, insomnia,...

Introduction: Autoimmune polyglandular syndromes (APS) are rare polyendocrinopathies characterized by the failure of several endocrine glands as well as nonendocrine organs, caused by an immune-mediated destruction of endocrine tissues. The type IIIa APS is the association of thyroid autoimmune diseases, type 1 diabetes mellitus and other autoimmune conditions excluding Addison’s disease and hypoparathyroidism. Herein, we report the case of autoimmune hypothyroidism assoc...

Introduction: Excess of abdominal fat may disturb metabolic parameters that affect insulin level and may lead to menstrual disorders, consecutively to disturbance in sex steroids production. The aim is to link the metabolic hormones in abdominal obesity, with reproductive axis hormones in women at age.Patients and methods: 85 no menopausal women aged between 17 and 52 were recruited: 62 with abdominal obesity (BMI >30 kg/m2 and waist circu...

Introduction: The frequency of obesity is increasing in Algeria, insulin resistance is one of the consequences pathological of the abdominal obesity. The purpose of this work is to study the implication of the abdominal obesity in the insulinorésistance and the complications which arise by the latter.Materials and methods: The study is realised on 105 obese (85 women and 20 men) (BMI >30) and 55 thin (40 women and 15 men) with mean age 37.60&#17...

Introduction: Breast cancer is one of the diseases causing the most deaths in women worldwide. Obesity, especially in postmenopausal women is a definite risk factor due to hormonal imbalance mainly to the levels of circulating oestrogen. The aim was to record levels for some gonadal axis hormones in breast cancer treated obese women.Patients and methods: 81 women aged between 21 and 80 years 54 are diagnosed with breast cancer (BC) during postmenopausal ...

Background: Exacerbations are an important feature and outcome measure in chronic obstructive pulmonary disease (COPD). The objective of this study was to investigate the effect of supplementation of standard treatment (inhaled long-acting β2 agonists, anticholinergics and corticosteroids) with vitamin D on pulmonary function tests in patients with COPD exacerbation.Methods: Patients referred to hospital were divided into three groups receiving 0.25...

In this controlled study the BMD of Proximal femur in postmenopausal diabetic women were assessed in comparison to healthy postmenopausal controls.BMD results from 65 postmenopausal women, aged 45-65 years old, with diabetes type 2, were compared with 65 age-matched controls. Bone densitometry from proximal femur (neck, Ward, trochanter) was performed using Dual X-ray Absorptiometry (DEXA). Subjects were categorized as 'osteopenic-osteoporotic' if their...

Osteoporosis is one of the most common bone diseases whose complications, morbitidy and mortality impose direct and indirect expenses. Vitamin-D is one of the most important factors in calcium absorption for bone formation. In this study we have evaluated vit-D level and other calcium metabolism indicators in urban population of Tehran.In a cross-sectional study in winter 2001, 1231 normal persons; 20-69 years, 502 male and 724 female, among urban popula...